Involvement of 5-Lipoxygenase in the Corticosteroid-Dependent Amyloid Beta Formation: In Vitro and In Vivo Evidence

BACKGROUND: Numerous studies show that high circulating level of glucocorticosteroids is a biochemical characteristic of Alzheimer's disease (AD). These stress hormones can increase the amount of AD-like pathology in animal models of the disease. Since they also up-regulate the 5-Lipoxygenase (...

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Detalles Bibliográficos
Autores principales: Puccio, Simone, Chu, Jin, Praticò, Domenico
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017076/
https://www.ncbi.nlm.nih.gov/pubmed/21253592
http://dx.doi.org/10.1371/journal.pone.0015163

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017076/
https://www.ncbi.nlm.nih.gov/pubmed/21253592
http://dx.doi.org/10.1371/journal.pone.0015163

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