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Increased Memory Conversion of Naïve CD8 T Cells Activated during Late Phases of Acute Virus Infection Due to Decreased Cumulative Antigen Exposure

BACKGROUND: Memory CD8 T cells form an essential part of protective immunity against viral infections. Antigenic load, costimulation, CD4-help, cytokines and chemokines fluctuate during the course of an antiviral immune response thus affecting CD8 T cell activation and memory conversion. METHODOLOGY...

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Detalles Bibliográficos
Autores principales:	Fousteri, Georgia, Dave, Amy, Juedes, Amy, Juntti, Therese, Morin, Bret, Togher, Lisa, Farber, Donna L., von Herrath, Matthias
Formato:	Texto
Lenguaje:	English
Publicado:	Public Library of Science 2011
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017078/ https://www.ncbi.nlm.nih.gov/pubmed/21253594 http://dx.doi.org/10.1371/journal.pone.0014502

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