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Proliferating Cell Nuclear Antigen (PCNA) Regulates Primordial Follicle Assembly by Promoting Apoptosis of Oocytes in Fetal and Neonatal Mouse Ovaries

Primordial follicles, providing all the oocytes available to a female throughout her reproductive life, assemble in perinatal ovaries with individual oocytes surrounded by granulosa cells. In mammals including the mouse, most oocytes die by apoptosis during primordial follicle assembly, but factors...

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Detalles Bibliográficos
Autores principales: Xu, Bo, Hua, Juan, Zhang, Yuanwei, Jiang, Xiaohua, Zhang, Huan, Ma, Tieliang, Zheng, Wei, Sun, Rui, Shen, Wei, Sha, Jiahao, Cooke, Howard J., Shi, Qinghua
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017099/
https://www.ncbi.nlm.nih.gov/pubmed/21253613
http://dx.doi.org/10.1371/journal.pone.0016046