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Crystal Structure of Escherichia coli CusC, the Outer Membrane Component of a Heavy Metal Efflux Pump

BACKGROUND: While copper has essential functions as an enzymatic co-factor, excess copper ions are toxic for cells, necessitating mechanisms for regulating its levels. The cusCBFA operon of E. coli encodes a four-component efflux pump dedicated to the extrusion of Cu(I) and Ag(I) ions. METHODOLOGY/P...

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Detalles Bibliográficos
Autores principales: Kulathila, Rithika, Kulathila, Ragini, Indic, Mridhu, van den Berg, Bert
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017539/
https://www.ncbi.nlm.nih.gov/pubmed/21249122
http://dx.doi.org/10.1371/journal.pone.0015610

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