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Position-dependent effects on stability in tricyclo-DNA modified oligonucleotide duplexes
A series of oligodeoxyribonucleotides and oligoribonucleotides containing single and multiple tricyclo(tc)-nucleosides in various arrangements were prepared and the thermal and thermodynamic transition profiles of duplexes with complementary DNA and RNA evaluated. Tc-residues aligned in a non-contin...
| Autores principales: | , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017593/ https://www.ncbi.nlm.nih.gov/pubmed/20719742 http://dx.doi.org/10.1093/nar/gkq733 |