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Position-dependent effects on stability in tricyclo-DNA modified oligonucleotide duplexes

A series of oligodeoxyribonucleotides and oligoribonucleotides containing single and multiple tricyclo(tc)-nucleosides in various arrangements were prepared and the thermal and thermodynamic transition profiles of duplexes with complementary DNA and RNA evaluated. Tc-residues aligned in a non-contin...

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Detalles Bibliográficos
Autores principales:	Ittig, Damian, Gerber, Anna-Barbara, Leumann, Christian J.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Synthetic Biology and Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017593/ https://www.ncbi.nlm.nih.gov/pubmed/20719742 http://dx.doi.org/10.1093/nar/gkq733

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