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The splicing-factor related protein SFPQ/PSF interacts with RAD51D and is necessary for homology-directed repair and sister chromatid cohesion
DNA double-stranded breaks (DSBs) are among the most severe forms of DNA damage and responsible for chromosomal translocations that may lead to gene fusions. The RAD51 family plays an integral role in preserving genome stability by homology directed repair of DSBs. From a proteomics screen, we recen...
Autores principales: | Rajesh, Changanamkandath, Baker, Dustin K., Pierce, Andrew J., Pittman, Douglas L. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017596/ https://www.ncbi.nlm.nih.gov/pubmed/20813759 http://dx.doi.org/10.1093/nar/gkq738 |
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