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Improved deoxyribozymes for synthesis of covalently branched DNA and RNA
A covalently branched nucleic acid can be synthesized by joining the 2′-hydroxyl of the branch-site ribonucleotide of a DNA or RNA strand to the activated 5′-phosphorus of a separate DNA or RNA strand. We have previously used deoxyribozymes to synthesize several types of branched nucleic acids for e...
Autores principales: | Lee, Christine S., Mui, Timothy P., Silverman, Scott K. |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017605/ https://www.ncbi.nlm.nih.gov/pubmed/20739352 http://dx.doi.org/10.1093/nar/gkq753 |
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