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The many paths to frameshifting: kinetic modelling and analysis of the effects of different elongation steps on programmed –1 ribosomal frameshifting

Several important viruses including the human immunodeficiency virus type 1 (HIV-1) and the SARS-associated Coronavirus (SARS-CoV) employ programmed −1 ribosomal frameshifting (PRF) for their protein expression. Here, a kinetic framework is developed to describe −1 PRF. The model reveals three kinet...

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Detalles Bibliográficos
Autores principales:	Liao, Pei-Yu, Choi, Yong Seok, Dinman, Jonathan D., Lee, Kelvin H.
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	RNA
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017607/ https://www.ncbi.nlm.nih.gov/pubmed/20823091 http://dx.doi.org/10.1093/nar/gkq761

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