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Modular pathways for editing non-cognate amino acids by human cytoplasmic leucyl-tRNA synthetase

To prevent potential errors in protein synthesis, some aminoacyl-transfer RNA (tRNA) synthetases have evolved editing mechanisms to hydrolyze misactivated amino acids (pre-transfer editing) or misacylated tRNAs (post-transfer editing). Class Ia leucyl-tRNA synthetase (LeuRS) may misactivate various...

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Detalles Bibliográficos
Autores principales:	Chen, Xin, Ma, Jing-Jing, Tan, Min, Yao, Peng, Hu, Qing-Hua, Eriani, Gilbert, Wang, En-Duo
Formato:	Texto
Lenguaje:	English
Publicado:	Oxford University Press 2011
Materias:	Nucleic Acid Enzymes
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017609/ https://www.ncbi.nlm.nih.gov/pubmed/20805241 http://dx.doi.org/10.1093/nar/gkq763

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