Complete Atrioventricular Block Secondary to Bortezomib Use in Multiple Myeloma
Bortezomib is an inhibitor of 26S proteasome, which is an effective treatment for multiple myeloma. The common adverse effects of bortezomib are asthenic conditions, gastrointestinal disturbances, and peripheral neuropathy. Here we describe a patient with dyspnea and general weakness because of comp...
Autores principales: | , , , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
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Yonsei University College of Medicine
2011
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017698/ https://www.ncbi.nlm.nih.gov/pubmed/21155055 http://dx.doi.org/10.3349/ymj.2011.52.1.196 |
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author | Lee, Won-Seop Kim, Dae-Hyeok Shin, Sung-Hee Woo, Seoung-Il Kwan, Jun Park, Keum-Soo Park, Sang-Don Yi, Hyeon-Gyu Jeon, Sang-Hoon |
author_facet | Lee, Won-Seop Kim, Dae-Hyeok Shin, Sung-Hee Woo, Seoung-Il Kwan, Jun Park, Keum-Soo Park, Sang-Don Yi, Hyeon-Gyu Jeon, Sang-Hoon |
author_sort | Lee, Won-Seop |
collection | PubMed |
description | Bortezomib is an inhibitor of 26S proteasome, which is an effective treatment for multiple myeloma. The common adverse effects of bortezomib are asthenic conditions, gastrointestinal disturbances, and peripheral neuropathy. Here we describe a patient with dyspnea and general weakness because of complete atrioventricular block while receiving bortezomib. We immediately stopped bortezomib, and after inserting a permanent VDD pacemaker, the patients' symptoms disappeared. |
format | Text |
id | pubmed-3017698 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2011 |
publisher | Yonsei University College of Medicine |
record_format | MEDLINE/PubMed |
spelling | pubmed-30176982011-01-10 Complete Atrioventricular Block Secondary to Bortezomib Use in Multiple Myeloma Lee, Won-Seop Kim, Dae-Hyeok Shin, Sung-Hee Woo, Seoung-Il Kwan, Jun Park, Keum-Soo Park, Sang-Don Yi, Hyeon-Gyu Jeon, Sang-Hoon Yonsei Med J Case Report Bortezomib is an inhibitor of 26S proteasome, which is an effective treatment for multiple myeloma. The common adverse effects of bortezomib are asthenic conditions, gastrointestinal disturbances, and peripheral neuropathy. Here we describe a patient with dyspnea and general weakness because of complete atrioventricular block while receiving bortezomib. We immediately stopped bortezomib, and after inserting a permanent VDD pacemaker, the patients' symptoms disappeared. Yonsei University College of Medicine 2011-01-01 2010-11-30 /pmc/articles/PMC3017698/ /pubmed/21155055 http://dx.doi.org/10.3349/ymj.2011.52.1.196 Text en © Copyright: Yonsei University College of Medicine 2011 http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Lee, Won-Seop Kim, Dae-Hyeok Shin, Sung-Hee Woo, Seoung-Il Kwan, Jun Park, Keum-Soo Park, Sang-Don Yi, Hyeon-Gyu Jeon, Sang-Hoon Complete Atrioventricular Block Secondary to Bortezomib Use in Multiple Myeloma |
title | Complete Atrioventricular Block Secondary to Bortezomib Use in Multiple Myeloma |
title_full | Complete Atrioventricular Block Secondary to Bortezomib Use in Multiple Myeloma |
title_fullStr | Complete Atrioventricular Block Secondary to Bortezomib Use in Multiple Myeloma |
title_full_unstemmed | Complete Atrioventricular Block Secondary to Bortezomib Use in Multiple Myeloma |
title_short | Complete Atrioventricular Block Secondary to Bortezomib Use in Multiple Myeloma |
title_sort | complete atrioventricular block secondary to bortezomib use in multiple myeloma |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3017698/ https://www.ncbi.nlm.nih.gov/pubmed/21155055 http://dx.doi.org/10.3349/ymj.2011.52.1.196 |
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