Terahertz pulsed imaging of knee cartilage

Osteoarthritis (OA) is a common form of arthritis caused by cartilage degeneration. In this paper, we investigate the potential use of terahertz (THz) pulsed imaging to quantitatively measure the early symptoms of OA in an animal model. THz images of excised rabbit femoral condyles were taken. We ob...

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Autores principales: Kan, Wai-Chi, Lee, Win-Sze, Cheung, Wing-Hoi, Wallace, Vincent P., Pickwell-MacPherson, Emma
Formato: Texto
Lenguaje:English
Publicado: Optical Society of America 2010
Materias:
Spectroscopic Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018044/
https://www.ncbi.nlm.nih.gov/pubmed/21258522
http://dx.doi.org/10.1364/BOE.1.000967
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author Kan, Wai-Chi
Lee, Win-Sze
Cheung, Wing-Hoi
Wallace, Vincent P.
Pickwell-MacPherson, Emma
author_facet Kan, Wai-Chi
Lee, Win-Sze
Cheung, Wing-Hoi
Wallace, Vincent P.
Pickwell-MacPherson, Emma
author_sort Kan, Wai-Chi
collection PubMed
description Osteoarthritis (OA) is a common form of arthritis caused by cartilage degeneration. In this paper, we investigate the potential use of terahertz (THz) pulsed imaging to quantitatively measure the early symptoms of OA in an animal model. THz images of excised rabbit femoral condyles were taken. We observe THz waves reflected off different layers within samples and demonstrate that the optical delay between reflections can give a quantitative measure of the thicknesses of particular tissues within cartilage.
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spelling pubmed-30180442011-01-21 Terahertz pulsed imaging of knee cartilage Kan, Wai-Chi Lee, Win-Sze Cheung, Wing-Hoi Wallace, Vincent P. Pickwell-MacPherson, Emma Biomed Opt Express Spectroscopic Diagnostics Osteoarthritis (OA) is a common form of arthritis caused by cartilage degeneration. In this paper, we investigate the potential use of terahertz (THz) pulsed imaging to quantitatively measure the early symptoms of OA in an animal model. THz images of excised rabbit femoral condyles were taken. We observe THz waves reflected off different layers within samples and demonstrate that the optical delay between reflections can give a quantitative measure of the thicknesses of particular tissues within cartilage. Optical Society of America 2010-09-20 /pmc/articles/PMC3018044/ /pubmed/21258522 http://dx.doi.org/10.1364/BOE.1.000967 Text en ©2010 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Spectroscopic Diagnostics
Kan, Wai-Chi
Lee, Win-Sze
Cheung, Wing-Hoi
Wallace, Vincent P.
Pickwell-MacPherson, Emma
Terahertz pulsed imaging of knee cartilage
title Terahertz pulsed imaging of knee cartilage
title_full Terahertz pulsed imaging of knee cartilage
title_fullStr Terahertz pulsed imaging of knee cartilage
title_full_unstemmed Terahertz pulsed imaging of knee cartilage
title_short Terahertz pulsed imaging of knee cartilage
title_sort terahertz pulsed imaging of knee cartilage
topic Spectroscopic Diagnostics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018044/
https://www.ncbi.nlm.nih.gov/pubmed/21258522
http://dx.doi.org/10.1364/BOE.1.000967
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AT wallacevincentp terahertzpulsedimagingofkneecartilage
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