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Fluorescence lifetime optical tomography with Discontinuous Galerkin discretisation scheme

We develop discontinuous Galerkin framework for solving direct and inverse problems in fluorescence diffusion optical tomography in turbid media. We show the advantages and the disadvantages of this method by comparing it with previously developed framework based on the finite volume discretization....

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Detalles Bibliográficos
Autores principales: Soloviev, Vadim Y., D'Andrea, Cosimo, Mohan, P. Surya, Valentini, Gianluca, Cubeddu, Rinaldo, Arridge, Simon R.
Formato: Texto
Lenguaje:English
Publicado: Optical Society of America 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018046/
https://www.ncbi.nlm.nih.gov/pubmed/21258525
http://dx.doi.org/10.1364/BOE.1.000998
Descripción
Sumario:We develop discontinuous Galerkin framework for solving direct and inverse problems in fluorescence diffusion optical tomography in turbid media. We show the advantages and the disadvantages of this method by comparing it with previously developed framework based on the finite volume discretization. The reconstruction algorithm was used with time-gated experimental dataset acquired by imaging a highly scattering cylindrical phantom concealing small fluorescent tubes. Optical parameters, quantum yield and lifetime were simultaneously reconstructed. Reconstruction results are presented and discussed.