Fluorescence lifetime optical tomography with Discontinuous Galerkin discretisation scheme

We develop discontinuous Galerkin framework for solving direct and inverse problems in fluorescence diffusion optical tomography in turbid media. We show the advantages and the disadvantages of this method by comparing it with previously developed framework based on the finite volume discretization....

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Detalles Bibliográficos
Autores principales: Soloviev, Vadim Y., D'Andrea, Cosimo, Mohan, P. Surya, Valentini, Gianluca, Cubeddu, Rinaldo, Arridge, Simon R.
Formato: Texto
Lenguaje:English
Publicado: Optical Society of America 2010
Materias:
Image Reconstruction and Inverse Problems
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018046/
https://www.ncbi.nlm.nih.gov/pubmed/21258525
http://dx.doi.org/10.1364/BOE.1.000998
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author Soloviev, Vadim Y.
D'Andrea, Cosimo
Mohan, P. Surya
Valentini, Gianluca
Cubeddu, Rinaldo
Arridge, Simon R.
author_facet Soloviev, Vadim Y.
D'Andrea, Cosimo
Mohan, P. Surya
Valentini, Gianluca
Cubeddu, Rinaldo
Arridge, Simon R.
author_sort Soloviev, Vadim Y.
collection PubMed
description We develop discontinuous Galerkin framework for solving direct and inverse problems in fluorescence diffusion optical tomography in turbid media. We show the advantages and the disadvantages of this method by comparing it with previously developed framework based on the finite volume discretization. The reconstruction algorithm was used with time-gated experimental dataset acquired by imaging a highly scattering cylindrical phantom concealing small fluorescent tubes. Optical parameters, quantum yield and lifetime were simultaneously reconstructed. Reconstruction results are presented and discussed.
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spelling pubmed-30180462011-01-21 Fluorescence lifetime optical tomography with Discontinuous Galerkin discretisation scheme Soloviev, Vadim Y. D'Andrea, Cosimo Mohan, P. Surya Valentini, Gianluca Cubeddu, Rinaldo Arridge, Simon R. Biomed Opt Express Image Reconstruction and Inverse Problems We develop discontinuous Galerkin framework for solving direct and inverse problems in fluorescence diffusion optical tomography in turbid media. We show the advantages and the disadvantages of this method by comparing it with previously developed framework based on the finite volume discretization. The reconstruction algorithm was used with time-gated experimental dataset acquired by imaging a highly scattering cylindrical phantom concealing small fluorescent tubes. Optical parameters, quantum yield and lifetime were simultaneously reconstructed. Reconstruction results are presented and discussed. Optical Society of America 2010-09-20 /pmc/articles/PMC3018046/ /pubmed/21258525 http://dx.doi.org/10.1364/BOE.1.000998 Text en ©2010 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Image Reconstruction and Inverse Problems
Soloviev, Vadim Y.
D'Andrea, Cosimo
Mohan, P. Surya
Valentini, Gianluca
Cubeddu, Rinaldo
Arridge, Simon R.
Fluorescence lifetime optical tomography with Discontinuous Galerkin discretisation scheme
title Fluorescence lifetime optical tomography with Discontinuous Galerkin discretisation scheme
title_full Fluorescence lifetime optical tomography with Discontinuous Galerkin discretisation scheme
title_fullStr Fluorescence lifetime optical tomography with Discontinuous Galerkin discretisation scheme
title_full_unstemmed Fluorescence lifetime optical tomography with Discontinuous Galerkin discretisation scheme
title_short Fluorescence lifetime optical tomography with Discontinuous Galerkin discretisation scheme
title_sort fluorescence lifetime optical tomography with discontinuous galerkin discretisation scheme
topic Image Reconstruction and Inverse Problems
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018046/
https://www.ncbi.nlm.nih.gov/pubmed/21258525
http://dx.doi.org/10.1364/BOE.1.000998
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