Fiber-optic and articulating arm implementations of laminar optical tomography for clinical applications

Laminar optical tomography (LOT) is a recently developed technique for depth-resolved in vivo imaging of absorption and fluorescence contrast. Until now, LOT has been implemented in a benchtop configuration, limiting accessibility to tissues and restricting imaging applications. Here we report on LO...

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Detalles Bibliográficos
Autores principales: Burgess, Sean A., Ratner, Désirée, Chen, Brenda R., Hillman, Elizabeth M. C.
Formato: Texto
Lenguaje:English
Publicado: Optical Society of America 2010
Materias:
Clinical Instrumentation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018052/
https://www.ncbi.nlm.nih.gov/pubmed/21258509
http://dx.doi.org/10.1364/BOE.1.000780
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author Burgess, Sean A.
Ratner, Désirée
Chen, Brenda R.
Hillman, Elizabeth M. C.
author_facet Burgess, Sean A.
Ratner, Désirée
Chen, Brenda R.
Hillman, Elizabeth M. C.
author_sort Burgess, Sean A.
collection PubMed
description Laminar optical tomography (LOT) is a recently developed technique for depth-resolved in vivo imaging of absorption and fluorescence contrast. Until now, LOT has been implemented in a benchtop configuration, limiting accessibility to tissues and restricting imaging applications. Here we report on LOT implemented through an articulating arm and a fiber optic image bundle allowing flexible imaging for a range of clinical applications. We quantify the performance of these two implementations by imaging a tissue mimicking phantom.
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spelling pubmed-30180522011-01-21 Fiber-optic and articulating arm implementations of laminar optical tomography for clinical applications Burgess, Sean A. Ratner, Désirée Chen, Brenda R. Hillman, Elizabeth M. C. Biomed Opt Express Clinical Instrumentation Laminar optical tomography (LOT) is a recently developed technique for depth-resolved in vivo imaging of absorption and fluorescence contrast. Until now, LOT has been implemented in a benchtop configuration, limiting accessibility to tissues and restricting imaging applications. Here we report on LOT implemented through an articulating arm and a fiber optic image bundle allowing flexible imaging for a range of clinical applications. We quantify the performance of these two implementations by imaging a tissue mimicking phantom. Optical Society of America 2010-09-02 /pmc/articles/PMC3018052/ /pubmed/21258509 http://dx.doi.org/10.1364/BOE.1.000780 Text en ©2010 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Clinical Instrumentation
Burgess, Sean A.
Ratner, Désirée
Chen, Brenda R.
Hillman, Elizabeth M. C.
Fiber-optic and articulating arm implementations of laminar optical tomography for clinical applications
title Fiber-optic and articulating arm implementations of laminar optical tomography for clinical applications
title_full Fiber-optic and articulating arm implementations of laminar optical tomography for clinical applications
title_fullStr Fiber-optic and articulating arm implementations of laminar optical tomography for clinical applications
title_full_unstemmed Fiber-optic and articulating arm implementations of laminar optical tomography for clinical applications
title_short Fiber-optic and articulating arm implementations of laminar optical tomography for clinical applications
title_sort fiber-optic and articulating arm implementations of laminar optical tomography for clinical applications
topic Clinical Instrumentation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018052/
https://www.ncbi.nlm.nih.gov/pubmed/21258509
http://dx.doi.org/10.1364/BOE.1.000780
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