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Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation

PURPOSE: The limbus and its stem cells are very important in the pathogenesis of pterygium. In this study, the efficacy of limbal stem cells and conjunctival autograft transplantation for the treatment of primary pterygium will be assessed. DESIGN: Prospective noncomparative cohort study. MATERIALS...

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Autores principales: Mahdy, Mohamed A. E. Soliman, Bhatia, Jagdish
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018101/
https://www.ncbi.nlm.nih.gov/pubmed/21234220
http://dx.doi.org/10.4103/0974-620X.48418
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author Mahdy, Mohamed A. E. Soliman
Bhatia, Jagdish
author_facet Mahdy, Mohamed A. E. Soliman
Bhatia, Jagdish
author_sort Mahdy, Mohamed A. E. Soliman
collection PubMed
description PURPOSE: The limbus and its stem cells are very important in the pathogenesis of pterygium. In this study, the efficacy of limbal stem cells and conjunctival autograft transplantation for the treatment of primary pterygium will be assessed. DESIGN: Prospective noncomparative cohort study. MATERIALS AND METHODS: Forty-two eyes of 42 patients with grade I-III primary pterygium were included in the study. Pterygium excision was performed followed by superotemporal limbal stem cells and conjunctival autograft transplantation in all cases. Recurrence of pterygium and complications within a mean follow-up period of 18.26 months (10-28 months) was studied. RESULTS: Recurrence of pterygium occurred in two eyes (2/42; 4.75%). No significant complications were noted. Apart from re-operation in the two recurrent cases, no further surgical interventions were needed in any case. CONCLUSIONS: Limbal stem cells and conjunctival autograft transplantation is a safe and effective technique for the treatment of different grades of pterygium. It is very useful in preventing pterygium recurrence, which is a major problem in pterygium surgery.
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spelling pubmed-30181012011-01-13 Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation Mahdy, Mohamed A. E. Soliman Bhatia, Jagdish Oman J Ophthalmol Original Article PURPOSE: The limbus and its stem cells are very important in the pathogenesis of pterygium. In this study, the efficacy of limbal stem cells and conjunctival autograft transplantation for the treatment of primary pterygium will be assessed. DESIGN: Prospective noncomparative cohort study. MATERIALS AND METHODS: Forty-two eyes of 42 patients with grade I-III primary pterygium were included in the study. Pterygium excision was performed followed by superotemporal limbal stem cells and conjunctival autograft transplantation in all cases. Recurrence of pterygium and complications within a mean follow-up period of 18.26 months (10-28 months) was studied. RESULTS: Recurrence of pterygium occurred in two eyes (2/42; 4.75%). No significant complications were noted. Apart from re-operation in the two recurrent cases, no further surgical interventions were needed in any case. CONCLUSIONS: Limbal stem cells and conjunctival autograft transplantation is a safe and effective technique for the treatment of different grades of pterygium. It is very useful in preventing pterygium recurrence, which is a major problem in pterygium surgery. Medknow Publications 2009 /pmc/articles/PMC3018101/ /pubmed/21234220 http://dx.doi.org/10.4103/0974-620X.48418 Text en © Oman Journal of Ophthalmology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Mahdy, Mohamed A. E. Soliman
Bhatia, Jagdish
Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation
title Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation
title_full Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation
title_fullStr Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation
title_full_unstemmed Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation
title_short Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation
title_sort treatment of primary pterygium: role of limbal stem cells and conjunctival autograft transplantation
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018101/
https://www.ncbi.nlm.nih.gov/pubmed/21234220
http://dx.doi.org/10.4103/0974-620X.48418
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