Cargando…
Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation
PURPOSE: The limbus and its stem cells are very important in the pathogenesis of pterygium. In this study, the efficacy of limbal stem cells and conjunctival autograft transplantation for the treatment of primary pterygium will be assessed. DESIGN: Prospective noncomparative cohort study. MATERIALS...
Autores principales: | , |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications
2009
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018101/ https://www.ncbi.nlm.nih.gov/pubmed/21234220 http://dx.doi.org/10.4103/0974-620X.48418 |
_version_ | 1782196022466838528 |
---|---|
author | Mahdy, Mohamed A. E. Soliman Bhatia, Jagdish |
author_facet | Mahdy, Mohamed A. E. Soliman Bhatia, Jagdish |
author_sort | Mahdy, Mohamed A. E. Soliman |
collection | PubMed |
description | PURPOSE: The limbus and its stem cells are very important in the pathogenesis of pterygium. In this study, the efficacy of limbal stem cells and conjunctival autograft transplantation for the treatment of primary pterygium will be assessed. DESIGN: Prospective noncomparative cohort study. MATERIALS AND METHODS: Forty-two eyes of 42 patients with grade I-III primary pterygium were included in the study. Pterygium excision was performed followed by superotemporal limbal stem cells and conjunctival autograft transplantation in all cases. Recurrence of pterygium and complications within a mean follow-up period of 18.26 months (10-28 months) was studied. RESULTS: Recurrence of pterygium occurred in two eyes (2/42; 4.75%). No significant complications were noted. Apart from re-operation in the two recurrent cases, no further surgical interventions were needed in any case. CONCLUSIONS: Limbal stem cells and conjunctival autograft transplantation is a safe and effective technique for the treatment of different grades of pterygium. It is very useful in preventing pterygium recurrence, which is a major problem in pterygium surgery. |
format | Text |
id | pubmed-3018101 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Medknow Publications |
record_format | MEDLINE/PubMed |
spelling | pubmed-30181012011-01-13 Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation Mahdy, Mohamed A. E. Soliman Bhatia, Jagdish Oman J Ophthalmol Original Article PURPOSE: The limbus and its stem cells are very important in the pathogenesis of pterygium. In this study, the efficacy of limbal stem cells and conjunctival autograft transplantation for the treatment of primary pterygium will be assessed. DESIGN: Prospective noncomparative cohort study. MATERIALS AND METHODS: Forty-two eyes of 42 patients with grade I-III primary pterygium were included in the study. Pterygium excision was performed followed by superotemporal limbal stem cells and conjunctival autograft transplantation in all cases. Recurrence of pterygium and complications within a mean follow-up period of 18.26 months (10-28 months) was studied. RESULTS: Recurrence of pterygium occurred in two eyes (2/42; 4.75%). No significant complications were noted. Apart from re-operation in the two recurrent cases, no further surgical interventions were needed in any case. CONCLUSIONS: Limbal stem cells and conjunctival autograft transplantation is a safe and effective technique for the treatment of different grades of pterygium. It is very useful in preventing pterygium recurrence, which is a major problem in pterygium surgery. Medknow Publications 2009 /pmc/articles/PMC3018101/ /pubmed/21234220 http://dx.doi.org/10.4103/0974-620X.48418 Text en © Oman Journal of Ophthalmology http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Mahdy, Mohamed A. E. Soliman Bhatia, Jagdish Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation |
title | Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation |
title_full | Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation |
title_fullStr | Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation |
title_full_unstemmed | Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation |
title_short | Treatment of primary pterygium: Role of limbal stem cells and conjunctival autograft transplantation |
title_sort | treatment of primary pterygium: role of limbal stem cells and conjunctival autograft transplantation |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018101/ https://www.ncbi.nlm.nih.gov/pubmed/21234220 http://dx.doi.org/10.4103/0974-620X.48418 |
work_keys_str_mv | AT mahdymohamedaesoliman treatmentofprimarypterygiumroleoflimbalstemcellsandconjunctivalautografttransplantation AT bhatiajagdish treatmentofprimarypterygiumroleoflimbalstemcellsandconjunctivalautografttransplantation |