Two-parameter angular light scatter collection for microfluidic flow cytometry by unique waveguide structures

Waveguide numerical aperture restrictions and light-blocking elements are used to create a microfluidic cytometer with both illumination and two-parameter light scatter collection systems integrated on-chip. Good forward scatter coefficients of variation (9.7-18.3%) are achieved for polystyrene bead...

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Detalles Bibliográficos
Autores principales: Godin, Jessica, Lo, Yu-Hwa
Formato: Texto
Lenguaje:English
Publicado: Optical Society of America 2010
Materias:
Microfluidics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018119/
https://www.ncbi.nlm.nih.gov/pubmed/21258563
http://dx.doi.org/10.1364/BOE.1.001472
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author Godin, Jessica
Lo, Yu-Hwa
author_facet Godin, Jessica
Lo, Yu-Hwa
author_sort Godin, Jessica
collection PubMed
description Waveguide numerical aperture restrictions and light-blocking elements are used to create a microfluidic cytometer with both illumination and two-parameter light scatter collection systems integrated on-chip. Good forward scatter coefficients of variation (9.7-18.3%) are achieved for polystyrene beads under a reasonably high flow rate (28 cm/s) using a greatly simplified optical system.
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spelling pubmed-30181192011-01-21 Two-parameter angular light scatter collection for microfluidic flow cytometry by unique waveguide structures Godin, Jessica Lo, Yu-Hwa Biomed Opt Express Microfluidics Waveguide numerical aperture restrictions and light-blocking elements are used to create a microfluidic cytometer with both illumination and two-parameter light scatter collection systems integrated on-chip. Good forward scatter coefficients of variation (9.7-18.3%) are achieved for polystyrene beads under a reasonably high flow rate (28 cm/s) using a greatly simplified optical system. Optical Society of America 2010-11-22 /pmc/articles/PMC3018119/ /pubmed/21258563 http://dx.doi.org/10.1364/BOE.1.001472 Text en ©2010 Optical Society of America http://creativecommons.org/licenses/by-nc-nd/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-No Derivative Works 3.0 Unported License, which permits download and redistribution, provided that the original work is properly cited. This license restricts the article from being modified or used commercially.
spellingShingle Microfluidics
Godin, Jessica
Lo, Yu-Hwa
Two-parameter angular light scatter collection for microfluidic flow cytometry by unique waveguide structures
title Two-parameter angular light scatter collection for microfluidic flow cytometry by unique waveguide structures
title_full Two-parameter angular light scatter collection for microfluidic flow cytometry by unique waveguide structures
title_fullStr Two-parameter angular light scatter collection for microfluidic flow cytometry by unique waveguide structures
title_full_unstemmed Two-parameter angular light scatter collection for microfluidic flow cytometry by unique waveguide structures
title_short Two-parameter angular light scatter collection for microfluidic flow cytometry by unique waveguide structures
title_sort two-parameter angular light scatter collection for microfluidic flow cytometry by unique waveguide structures
topic Microfluidics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018119/
https://www.ncbi.nlm.nih.gov/pubmed/21258563
http://dx.doi.org/10.1364/BOE.1.001472
work_keys_str_mv AT godinjessica twoparameterangularlightscattercollectionformicrofluidicflowcytometrybyuniquewaveguidestructures
AT loyuhwa twoparameterangularlightscattercollectionformicrofluidicflowcytometrybyuniquewaveguidestructures

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