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Design principles of nuclear receptor signaling: how complex networking improves signal transduction
The topology of nuclear receptor (NR) signaling is captured in a systems biological graphical notation. This enables us to identify a number of ‘design’ aspects of the topology of these networks that might appear unnecessarily complex or even functionally paradoxical. In realistic kinetic models of...
| Autores principales: | , , , , , , , , , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
European Molecular Biology Organization
2010
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018161/ https://www.ncbi.nlm.nih.gov/pubmed/21179018 http://dx.doi.org/10.1038/msb.2010.102 |