Integrative model of genomic factors for determining binding site selection by estrogen receptor-α

A major question in transcription factor (TF) biology is why a TF binds to only a small fraction of motif eligible binding sites in the genome. Using the estrogen receptor-α as a model system, we sought to explicitly define parameters that determine TF-binding site selection. By examining 12 genetic...

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Detalles Bibliográficos
Autores principales: Joseph, Roy, Orlov, Yuriy L, Huss, Mikael, Sun, Wenjie, Li Kong, Say, Ukil, Leena, Fu Pan, You, Li, Guoliang, Lim, Michael, Thomsen, Jane S, Ruan, Yijun, Clarke, Neil D, Prabhakar, Shyam, Cheung, Edwin, Liu, Edison T
Formato: Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2010
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018168/
https://www.ncbi.nlm.nih.gov/pubmed/21179027
http://dx.doi.org/10.1038/msb.2010.109

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