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Evolution, genomic analysis, and reconstruction of isobutanol tolerance in Escherichia coli

Escherichia coli has been engineered to produce isobutanol, with titers reaching greater than the toxicity level. However, the specific effects of isobutanol on the cell have never been fully understood. Here, we aim to identify genotype–phenotype relationships in isobutanol response. An isobutanol-...

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Detalles Bibliográficos
Autores principales: Atsumi, Shota, Wu, Tung-Yun, Machado, Iara M P, Huang, Wei-Chih, Chen, Pao-Yang, Pellegrini, Matteo, Liao, James C
Formato: Texto
Lenguaje:English
Publicado: Nature Publishing Group 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018172/
https://www.ncbi.nlm.nih.gov/pubmed/21179021
http://dx.doi.org/10.1038/msb.2010.98