PICK1 regulates the trafficking of ASIC1a and acidotoxicity in a BAR domain lipid binding-dependent manner

BACKGROUND: Acid-sensing ion channel 1a (ASIC1a) is the major ASIC subunit determining acid-activated currents in brain neurons. Recent studies show that ASIC1a play critical roles in acid-induced cell toxicity. While these studies raise the importance of ASIC1a in diseases, mechanisms for ASIC1a tr...

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Detalles Bibliográficos
Autores principales: Jin, Wenying, Shen, Chong, Jing, Lan, Zha, Xiang-ming, Xia, Jun
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018362/
https://www.ncbi.nlm.nih.gov/pubmed/21176140
http://dx.doi.org/10.1186/1756-6606-3-39

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018362/
https://www.ncbi.nlm.nih.gov/pubmed/21176140
http://dx.doi.org/10.1186/1756-6606-3-39

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