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Clustering by genetic ancestry using genome-wide SNP data
BACKGROUND: Population stratification can cause spurious associations in a genome-wide association study (GWAS), and occurs when differences in allele frequencies of single nucleotide polymorphisms (SNPs) are due to ancestral differences between cases and controls rather than the trait of interest....
Autores principales: | Solovieff, Nadia, Hartley, Stephen W, Baldwin, Clinton T, Perls, Thomas T, Steinberg, Martin H, Sebastiani, Paola |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018397/ https://www.ncbi.nlm.nih.gov/pubmed/21143920 http://dx.doi.org/10.1186/1471-2156-11-108 |
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