Soluble CD40 ligand-activated human peripheral B cells as surrogated antigen presenting cells: A preliminary approach for anti-HBV immunotherapy

BACKGROUND: We aimed to clarify whether soluble CD40 ligand (sCD40L) activated B cells may be loaded with HBcAg18-27 peptide and served as antigen-producing cells (APCs) to induce HBV-specific cytolytic T lymphocytes (CTLs). RESULTS: Human B cells could be cultured in the presence of sCD40L up to 54...

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Detalles Bibliográficos
Autores principales: Wu, Chao, Liu, Yong, Zhao, Qi, Chen, Guangmei, Chen, Junhao, Yan, Xiaomin, Zhou, Yi-Hua, Huang, Zuhu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018399/
https://www.ncbi.nlm.nih.gov/pubmed/21176236
http://dx.doi.org/10.1186/1743-422X-7-370

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