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Fractalkine receptor (CX(3)CR1) deficiency sensitizes mice to the behavioral changes induced by lipopolysaccharide
BACKGROUND: Interactions between fractalkine (CX(3)CL1) and fractalkine receptor (CX(3)CR1) regulate microglial activation in the CNS. Recent findings indicate that age-associated impairments in CX(3)CL1 and CX(3)CR1 are directly associated with exaggerated microglial activation and an impaired reco...
Autores principales: | , , , , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018416/ https://www.ncbi.nlm.nih.gov/pubmed/21167054 http://dx.doi.org/10.1186/1742-2094-7-93 |