MicroRNA Controlled Adenovirus Mediates Anti-Cancer Efficacy without Affecting Endogenous MicroRNA Activity

MicroRNAs are small non-coding RNA molecules that regulate mRNA translation and stability by binding to complementary sequences usually within the 3′ un-translated region (UTR). We have previously shown that the hepatic toxicity caused by wild-type Adenovirus 5 (Ad5WT) in mice can be prevented by in...

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Detalles Bibliográficos
Autores principales: Cawood, Ryan, Wong, Suet-Ling, Di, Ying, Baban, Dilair F., Seymour, Leonard W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018484/
https://www.ncbi.nlm.nih.gov/pubmed/21264344
http://dx.doi.org/10.1371/journal.pone.0016152

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018484/
https://www.ncbi.nlm.nih.gov/pubmed/21264344
http://dx.doi.org/10.1371/journal.pone.0016152

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