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Meeting Report: Estimating the Benefits of Reducing Hazardous Air Pollutants—Summary of 2009 Workshop and Future Considerations

BACKGROUND: Quantifying the benefits of reducing hazardous air pollutants (HAPs, or air toxics) has been limited by gaps in toxicological data, uncertainties in extrapolating results from high-dose animal experiments to estimate human effects at lower doses, limited ambient and personal exposure mon...

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Autores principales: Gwinn, Maureen R., Craig, Jeneva, Axelrad, Daniel A., Cook, Rich, Dockins, Chris, Fann, Neal, Fegley, Robert, Guinnup, David E., Helfand, Gloria, Hubbell, Bryan, Mazur, Sarah L., Palma, Ted, Smith, Roy L., Vandenberg, John, Sonawane, Babasaheb
Formato: Texto
Lenguaje:English
Publicado: National Institute of Environmental Health Sciences 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018491/
https://www.ncbi.nlm.nih.gov/pubmed/20920952
http://dx.doi.org/10.1289/ehp.1002468
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author Gwinn, Maureen R.
Craig, Jeneva
Axelrad, Daniel A.
Cook, Rich
Dockins, Chris
Fann, Neal
Fegley, Robert
Guinnup, David E.
Helfand, Gloria
Hubbell, Bryan
Mazur, Sarah L.
Palma, Ted
Smith, Roy L.
Vandenberg, John
Sonawane, Babasaheb
author_facet Gwinn, Maureen R.
Craig, Jeneva
Axelrad, Daniel A.
Cook, Rich
Dockins, Chris
Fann, Neal
Fegley, Robert
Guinnup, David E.
Helfand, Gloria
Hubbell, Bryan
Mazur, Sarah L.
Palma, Ted
Smith, Roy L.
Vandenberg, John
Sonawane, Babasaheb
author_sort Gwinn, Maureen R.
collection PubMed
description BACKGROUND: Quantifying the benefits of reducing hazardous air pollutants (HAPs, or air toxics) has been limited by gaps in toxicological data, uncertainties in extrapolating results from high-dose animal experiments to estimate human effects at lower doses, limited ambient and personal exposure monitoring data, and insufficient economic research to support valuation of the health impacts often associated with exposure to individual air toxics. OBJECTIVES: To address some of these issues, the U.S. Environmental Protection Agency held the Workshop on Estimating the Benefits of Reducing Hazardous Air Pollutants (HAPs) in Washington, DC, from 30 April to 1 May 2009. DISCUSSION: Experts from multiple disciplines discussed how best to move forward on air toxics benefits assessment, with a focus on developing near-term capability to conduct quantitative benefits assessment. Proposed methodologies involved analysis of data-rich pollutants and application of this analysis to other pollutants, using dose–response modeling of animal data for estimating benefits to humans, determining dose-equivalence relationships for different chemicals with similar health effects, and analysis similar to that used for criteria pollutants. Limitations and uncertainties in economic valuation of benefits assessment for HAPS were discussed as well. CONCLUSIONS: These discussions highlighted the complexities in estimating the benefits of reducing air toxics, and participants agreed that alternative methods for benefits assessment of HAPs are needed. Recommendations included clearly defining the key priorities of the Clean Air Act air toxics program to identify the most effective approaches for HAPs benefits analysis, focusing on susceptible and vulnerable populations, and improving dose–response estimation for quantification of benefits.
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spelling pubmed-30184912011-02-10 Meeting Report: Estimating the Benefits of Reducing Hazardous Air Pollutants—Summary of 2009 Workshop and Future Considerations Gwinn, Maureen R. Craig, Jeneva Axelrad, Daniel A. Cook, Rich Dockins, Chris Fann, Neal Fegley, Robert Guinnup, David E. Helfand, Gloria Hubbell, Bryan Mazur, Sarah L. Palma, Ted Smith, Roy L. Vandenberg, John Sonawane, Babasaheb Environ Health Perspect Research BACKGROUND: Quantifying the benefits of reducing hazardous air pollutants (HAPs, or air toxics) has been limited by gaps in toxicological data, uncertainties in extrapolating results from high-dose animal experiments to estimate human effects at lower doses, limited ambient and personal exposure monitoring data, and insufficient economic research to support valuation of the health impacts often associated with exposure to individual air toxics. OBJECTIVES: To address some of these issues, the U.S. Environmental Protection Agency held the Workshop on Estimating the Benefits of Reducing Hazardous Air Pollutants (HAPs) in Washington, DC, from 30 April to 1 May 2009. DISCUSSION: Experts from multiple disciplines discussed how best to move forward on air toxics benefits assessment, with a focus on developing near-term capability to conduct quantitative benefits assessment. Proposed methodologies involved analysis of data-rich pollutants and application of this analysis to other pollutants, using dose–response modeling of animal data for estimating benefits to humans, determining dose-equivalence relationships for different chemicals with similar health effects, and analysis similar to that used for criteria pollutants. Limitations and uncertainties in economic valuation of benefits assessment for HAPS were discussed as well. CONCLUSIONS: These discussions highlighted the complexities in estimating the benefits of reducing air toxics, and participants agreed that alternative methods for benefits assessment of HAPs are needed. Recommendations included clearly defining the key priorities of the Clean Air Act air toxics program to identify the most effective approaches for HAPs benefits analysis, focusing on susceptible and vulnerable populations, and improving dose–response estimation for quantification of benefits. National Institute of Environmental Health Sciences 2011-01 2010-10-04 /pmc/articles/PMC3018491/ /pubmed/20920952 http://dx.doi.org/10.1289/ehp.1002468 Text en http://creativecommons.org/publicdomain/mark/1.0/ Publication of EHP lies in the public domain and is therefore without copyright. All text from EHP may be reprinted freely. Use of materials published in EHP should be acknowledged (for example, ?Reproduced with permission from Environmental Health Perspectives?); pertinent reference information should be provided for the article from which the material was reproduced. Articles from EHP, especially the News section, may contain photographs or illustrations copyrighted by other commercial organizations or individuals that may not be used without obtaining prior approval from the holder of the copyright.
spellingShingle Research
Gwinn, Maureen R.
Craig, Jeneva
Axelrad, Daniel A.
Cook, Rich
Dockins, Chris
Fann, Neal
Fegley, Robert
Guinnup, David E.
Helfand, Gloria
Hubbell, Bryan
Mazur, Sarah L.
Palma, Ted
Smith, Roy L.
Vandenberg, John
Sonawane, Babasaheb
Meeting Report: Estimating the Benefits of Reducing Hazardous Air Pollutants—Summary of 2009 Workshop and Future Considerations
title Meeting Report: Estimating the Benefits of Reducing Hazardous Air Pollutants—Summary of 2009 Workshop and Future Considerations
title_full Meeting Report: Estimating the Benefits of Reducing Hazardous Air Pollutants—Summary of 2009 Workshop and Future Considerations
title_fullStr Meeting Report: Estimating the Benefits of Reducing Hazardous Air Pollutants—Summary of 2009 Workshop and Future Considerations
title_full_unstemmed Meeting Report: Estimating the Benefits of Reducing Hazardous Air Pollutants—Summary of 2009 Workshop and Future Considerations
title_short Meeting Report: Estimating the Benefits of Reducing Hazardous Air Pollutants—Summary of 2009 Workshop and Future Considerations
title_sort meeting report: estimating the benefits of reducing hazardous air pollutants—summary of 2009 workshop and future considerations
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018491/
https://www.ncbi.nlm.nih.gov/pubmed/20920952
http://dx.doi.org/10.1289/ehp.1002468
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