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Long Isoforms of NRF1 Contribute to Arsenic-Induced Antioxidant Response in Human Keratinocytes
BACKGROUND: Human exposure to inorganic arsenic (iAs), a potent oxidative stressor, causes various dermal disorders, including hyperkeratosis and skin cancer. Nuclear factor–erythroid 2–related factor 1 (NRF1, also called NFE2L1) plays a critical role in regulating the expression of many antioxidant...
Autores principales: | Zhao, Rui, Hou, Yongyong, Xue, Peng, Woods, Courtney G., Fu, Jingqi, Feng, Bo, Guan, Dawei, Sun, Guifan, Chan, Jefferson Y., Waalkes, Michael P., Andersen, Melvin E., Pi, Jingbo |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
National Institute of Environmental Health Sciences
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018500/ https://www.ncbi.nlm.nih.gov/pubmed/20805060 http://dx.doi.org/10.1289/ehp.1002304 |
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