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Experimental Toxocara cati Infection in Gerbils and Rats

Mongolian gerbils and Wistar rats were inoculated orally with 240 and 2,500 Toxocara cati embryonated eggs, respectively, to evaluate the larval recovery in different tissues and organs, such as the liver, lungs, heart, kidney, and skeletal muscles after 5, 30, 49, 70, and 92 days post-infection (PI...

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Detalles Bibliográficos
Autores principales: Zibaei, Mohammad, Sadjjadi, Seyed Mahmoud, Uga, Shoji
Formato: Texto
Lenguaje:English
Publicado: The Korean Society for Parasitology 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018584/
https://www.ncbi.nlm.nih.gov/pubmed/21234237
http://dx.doi.org/10.3347/kjp.2010.48.4.331
Descripción
Sumario:Mongolian gerbils and Wistar rats were inoculated orally with 240 and 2,500 Toxocara cati embryonated eggs, respectively, to evaluate the larval recovery in different tissues and organs, such as the liver, lungs, heart, kidney, and skeletal muscles after 5, 30, 49, 70, and 92 days post-infection (PI). Larval recovery rates were 1.7-30.0% in Mongolian gerbils on days 5-92 PI and 0.2-3.8% in rats on the same days. These results indicate that Mongolian gerbils and Wistar rats are suitable experimental paratenic hosts for the study of neurological toxocariasis as well as visceral toxocariasis.