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Identifying cancer driver genes in tumor genome sequencing studies
Motivation: Major tumor sequencing projects have been conducted in the past few years to identify genes that contain ‘driver’ somatic mutations in tumor samples. These genes have been defined as those for which the non-silent mutation rate is significantly greater than a background mutation rate est...
| Autores principales: | , |
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| Formato: | Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2011
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018819/ https://www.ncbi.nlm.nih.gov/pubmed/21169372 http://dx.doi.org/10.1093/bioinformatics/btq630 |