Myeloma cells with asurophilic granules – an unusual morphological variant – case presentation

We present the case of an 80–year–old man who was admitted for anemia, back pain and progressive weakness. After a workup of clinical and laboratory data, the final diagnosis was multiple myeloma. The bone marrow aspirate revealed 53% myeloma cells with peculiar and rare morphological features: nume...

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Autores principales: Vlădăreanu, AM, Cîşleanu, D, Derveşteanu, M, Onisai, M, Bumbea, Horia, Radeşi, S, Begu, M, Băluţă, C
Formato: Texto
Lenguaje:English
Publicado: Carol Davila University Press 2008
Materias:
Case Presentation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018960/
https://www.ncbi.nlm.nih.gov/pubmed/20108484
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author Vlădăreanu, AM
Cîşleanu, D
Derveşteanu, M
Onisai, M
Bumbea, Horia
Radeşi, S
Begu, M
Băluţă, C
author_facet Vlădăreanu, AM
Cîşleanu, D
Derveşteanu, M
Onisai, M
Bumbea, Horia
Radeşi, S
Begu, M
Băluţă, C
author_sort Vlădăreanu, AM
collection PubMed
description We present the case of an 80–year–old man who was admitted for anemia, back pain and progressive weakness. After a workup of clinical and laboratory data, the final diagnosis was multiple myeloma. The bone marrow aspirate revealed 53% myeloma cells with peculiar and rare morphological features: numerous large asurophilic–bright red granules – mucopolizaccharides and immunoglobulins secreted and accumulated in the endoplasmic reticulum, typically known as Russel bodies.
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spelling pubmed-30189602011-03-03 Myeloma cells with asurophilic granules – an unusual morphological variant – case presentation Vlădăreanu, AM Cîşleanu, D Derveşteanu, M Onisai, M Bumbea, Horia Radeşi, S Begu, M Băluţă, C J Med Life Case Presentation We present the case of an 80–year–old man who was admitted for anemia, back pain and progressive weakness. After a workup of clinical and laboratory data, the final diagnosis was multiple myeloma. The bone marrow aspirate revealed 53% myeloma cells with peculiar and rare morphological features: numerous large asurophilic–bright red granules – mucopolizaccharides and immunoglobulins secreted and accumulated in the endoplasmic reticulum, typically known as Russel bodies. Carol Davila University Press 2008-02-15 2008-02-25 /pmc/articles/PMC3018960/ /pubmed/20108484 Text en ©Carol Davila University Press http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use,distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Presentation
Vlădăreanu, AM
Cîşleanu, D
Derveşteanu, M
Onisai, M
Bumbea, Horia
Radeşi, S
Begu, M
Băluţă, C
Myeloma cells with asurophilic granules – an unusual morphological variant – case presentation
title Myeloma cells with asurophilic granules – an unusual morphological variant – case presentation
title_full Myeloma cells with asurophilic granules – an unusual morphological variant – case presentation
title_fullStr Myeloma cells with asurophilic granules – an unusual morphological variant – case presentation
title_full_unstemmed Myeloma cells with asurophilic granules – an unusual morphological variant – case presentation
title_short Myeloma cells with asurophilic granules – an unusual morphological variant – case presentation
title_sort myeloma cells with asurophilic granules – an unusual morphological variant – case presentation
topic Case Presentation
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018960/
https://www.ncbi.nlm.nih.gov/pubmed/20108484
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