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The importance of residual renal function in chronic dialysed patients
In the last decade, many researches have reached to the conclusion that preservation of residual renal function (RRF) is important after initiating dialysis, as well as in the predialysis period. RRF has been proven to contribue to the quality of life of dialysis patients. Longer preservation of RRF...
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Formato: | Texto |
Lenguaje: | English |
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Carol Davila University Press
2009
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018976/ https://www.ncbi.nlm.nih.gov/pubmed/20108541 |
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author | Rădulescu, D Ferechide, D |
author_facet | Rădulescu, D Ferechide, D |
author_sort | Rădulescu, D |
collection | PubMed |
description | In the last decade, many researches have reached to the conclusion that preservation of residual renal function (RRF) is important after initiating dialysis, as well as in the predialysis period. RRF has been proven to contribue to the quality of life of dialysis patients. Longer preservation of RRF provides a better small and middle molecule removal, improved volemic status and arterial pressure control, diminished risk of vascular and valvular calcification due to better phosphate removal. Deterioration of RRF results in worsening of anemia, inflammation and malnutrition. It is now proven a direct relationship between RRF value and survival in dialysis patient. Several therapeutical intervention have been proven to ameliorate the decline of RRF in dialysis patients. Some of them are identical with those before initiating dialysis: ACE–inhibitors and/or angiotensin–receptor blockers, limiting the use of nephrotoxic drugs, avoiding contrast media procedures, adequate control of blood pressure. Others are specific for dialysis period: adequate dialysis dose, avoiding excessive ultrafiltration, preventing arterial hypotension during dialysis sessions, using biocompatible dialysis membranes, ultrapure water for dialysis, dietary interventions. |
format | Text |
id | pubmed-3018976 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2009 |
publisher | Carol Davila University Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-30189762011-03-03 The importance of residual renal function in chronic dialysed patients Rădulescu, D Ferechide, D J Med Life General Article In the last decade, many researches have reached to the conclusion that preservation of residual renal function (RRF) is important after initiating dialysis, as well as in the predialysis period. RRF has been proven to contribue to the quality of life of dialysis patients. Longer preservation of RRF provides a better small and middle molecule removal, improved volemic status and arterial pressure control, diminished risk of vascular and valvular calcification due to better phosphate removal. Deterioration of RRF results in worsening of anemia, inflammation and malnutrition. It is now proven a direct relationship between RRF value and survival in dialysis patient. Several therapeutical intervention have been proven to ameliorate the decline of RRF in dialysis patients. Some of them are identical with those before initiating dialysis: ACE–inhibitors and/or angiotensin–receptor blockers, limiting the use of nephrotoxic drugs, avoiding contrast media procedures, adequate control of blood pressure. Others are specific for dialysis period: adequate dialysis dose, avoiding excessive ultrafiltration, preventing arterial hypotension during dialysis sessions, using biocompatible dialysis membranes, ultrapure water for dialysis, dietary interventions. Carol Davila University Press 2009-04-15 2009-04-25 /pmc/articles/PMC3018976/ /pubmed/20108541 Text en ©Carol Davila University Press http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use,distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | General Article Rădulescu, D Ferechide, D The importance of residual renal function in chronic dialysed patients |
title | The importance of residual renal function in chronic dialysed patients
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title_full | The importance of residual renal function in chronic dialysed patients
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title_fullStr | The importance of residual renal function in chronic dialysed patients
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title_full_unstemmed | The importance of residual renal function in chronic dialysed patients
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title_short | The importance of residual renal function in chronic dialysed patients
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title_sort | importance of residual renal function in chronic dialysed patients |
topic | General Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3018976/ https://www.ncbi.nlm.nih.gov/pubmed/20108541 |
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