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Rheumatoid arthritis: travelling biological era a Romanian X–ray population

Background: rheumatoid arthritis (RA) is associated with loss of overall functionality of the locomotion system and it is connected with substantial economic losses. Objective: to describe the clinical characteristics and healthcare resource utilization characteristics and to analyze the correlation...

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Autores principales: Mogosan, C, Stoica, V, Mihai, C, Macovei, L, Ancuta, I, Ciofu, C, Stefanescu, F, Bojinca, M, Martin, A, Milicescu, M, Crisan, V, Banciu, M, Suteanu, S
Formato: Texto
Lenguaje:English
Publicado: Carol Davila University Press 2009
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019021/
https://www.ncbi.nlm.nih.gov/pubmed/20108756
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author Mogosan, C
Stoica, V
Mihai, C
Macovei, L
Ancuta, I
Ciofu, C
Stefanescu, F
Bojinca, M
Martin, A
Milicescu, M
Crisan, V
Banciu, M
Suteanu, S
author_facet Mogosan, C
Stoica, V
Mihai, C
Macovei, L
Ancuta, I
Ciofu, C
Stefanescu, F
Bojinca, M
Martin, A
Milicescu, M
Crisan, V
Banciu, M
Suteanu, S
author_sort Mogosan, C
collection PubMed
description Background: rheumatoid arthritis (RA) is associated with loss of overall functionality of the locomotion system and it is connected with substantial economic losses. Objective: to describe the clinical characteristics and healthcare resource utilization characteristics and to analyze the correlations in a cross–sectional sample of 206 patients in Romania. Method: RA cases have been enrolled from southern and western part of the country, covering a surface of 23 counties. Results: particularly in the literature data, Romanian RA patients become work disabled at 5.65 ± 5.99 years old after the diagnosis. At cohort level, retirement in the first year after RA diagnosis is of 22.9%. From those, 13% were treated with biologic DMARDs; those on non–biologic DMARDs were 28.6%. In oral therapy group the most prescribed drug is lefunomide (61.2%). RA has an important impact on pain, function and utility, influenced by social factors. Patients' follow up is often based on hospitalization. Conclusion: currently, when the clinician may choose for one certain therapy or another, the social influence is still overwhelming at all the evaluation levels in RA patients, as well as at economic impact.
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spelling pubmed-30190212011-03-03 Rheumatoid arthritis: travelling biological era a Romanian X–ray population Mogosan, C Stoica, V Mihai, C Macovei, L Ancuta, I Ciofu, C Stefanescu, F Bojinca, M Martin, A Milicescu, M Crisan, V Banciu, M Suteanu, S J Med Life General Article Background: rheumatoid arthritis (RA) is associated with loss of overall functionality of the locomotion system and it is connected with substantial economic losses. Objective: to describe the clinical characteristics and healthcare resource utilization characteristics and to analyze the correlations in a cross–sectional sample of 206 patients in Romania. Method: RA cases have been enrolled from southern and western part of the country, covering a surface of 23 counties. Results: particularly in the literature data, Romanian RA patients become work disabled at 5.65 ± 5.99 years old after the diagnosis. At cohort level, retirement in the first year after RA diagnosis is of 22.9%. From those, 13% were treated with biologic DMARDs; those on non–biologic DMARDs were 28.6%. In oral therapy group the most prescribed drug is lefunomide (61.2%). RA has an important impact on pain, function and utility, influenced by social factors. Patients' follow up is often based on hospitalization. Conclusion: currently, when the clinician may choose for one certain therapy or another, the social influence is still overwhelming at all the evaluation levels in RA patients, as well as at economic impact. Carol Davila University Press 2009-11-15 2009-11-25 /pmc/articles/PMC3019021/ /pubmed/20108756 Text en ©Carol Davila University Press http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle General Article
Mogosan, C
Stoica, V
Mihai, C
Macovei, L
Ancuta, I
Ciofu, C
Stefanescu, F
Bojinca, M
Martin, A
Milicescu, M
Crisan, V
Banciu, M
Suteanu, S
Rheumatoid arthritis: travelling biological era a Romanian X–ray population
title Rheumatoid arthritis: travelling biological era a Romanian X–ray population
title_full Rheumatoid arthritis: travelling biological era a Romanian X–ray population
title_fullStr Rheumatoid arthritis: travelling biological era a Romanian X–ray population
title_full_unstemmed Rheumatoid arthritis: travelling biological era a Romanian X–ray population
title_short Rheumatoid arthritis: travelling biological era a Romanian X–ray population
title_sort rheumatoid arthritis: travelling biological era a romanian x–ray population
topic General Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019021/
https://www.ncbi.nlm.nih.gov/pubmed/20108756
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