Conformation dependent monoclonal antibodies distinguish different replicating strains or conformers of prefibrillar Aβ oligomers

BACKGROUND: Age-related neurodegenerative diseases share a number of important pathological features, such as accumulation of misfolded proteins as amyloid oligomers and fibrils. Recent evidence suggests that soluble amyloid oligomers and not the insoluble amyloid fibrils may represent the primary p...

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Detalles Bibliográficos
Autores principales: Kayed, Rakez, Canto, Isabel, Breydo, Leonid, Rasool, Suhail, Lukacsovich , Tamas, Wu, Jessica, Albay, Ricardo, Pensalfini, Anna, Yeung, Stephen, Head, Elizabeth, Marsh, J Lawrence, Glabe, Charles
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019145/
https://www.ncbi.nlm.nih.gov/pubmed/21144050
http://dx.doi.org/10.1186/1750-1326-5-57

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