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Induction of autoantibodies against lung matrix proteins and smoke-induced inflammation in mice
BACKGROUND: Smoking is the major etiologic factor in COPD, yet the exact underlying pathogenetic mechanisms have not been elucidated. Since a few years, there is mounting evidence that a specific immune response, partly present as an autoimmune response, contributes to the pathogenesis of COPD. Incr...
Autores principales: | Brandsma, Corry-Anke, Timens, Wim, Geerlings, Marie, Jekel, Henrike, Postma, Dirkje S, Hylkema, Machteld N, Kerstjens, Huib AM |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019146/ https://www.ncbi.nlm.nih.gov/pubmed/21144028 http://dx.doi.org/10.1186/1471-2466-10-64 |
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