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Identification of Critical Residues of the Mycobacterial Dephosphocoenzyme A Kinase by Site-Directed Mutagenesis

Dephosphocoenzyme A kinase performs the transfer of the γ-phosphate of ATP to dephosphocoenzyme A, catalyzing the last step of coenzyme A biosynthesis. This enzyme belongs to the P-loop-containing NTP hydrolase superfamily, all members of which posses a three domain topology consisting of a CoA doma...

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Detalles Bibliográficos
Autores principales: Walia, Guneet, Gajendar, Komatireddy, Surolia, Avadhesha
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019153/
https://www.ncbi.nlm.nih.gov/pubmed/21264299
http://dx.doi.org/10.1371/journal.pone.0015228

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