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Crystal Structure of Spy0129, a Streptococcus pyogenes Class B Sortase Involved in Pilus Assembly

Sortase enzymes are cysteine transpeptidases that mediate the covalent attachment of substrate proteins to the cell walls of Gram-positive bacteria, and thereby play a crucial role in virulence, infection and colonisation by pathogens. Many cell-surface proteins are anchored by the housekeeping sort...

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Detalles Bibliográficos
Autores principales: Kang, Hae Joo, Coulibaly, Fasséli, Proft, Thomas, Baker, Edward N.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019223/
https://www.ncbi.nlm.nih.gov/pubmed/21264317
http://dx.doi.org/10.1371/journal.pone.0015969