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Modulation of the P-Glycoproein-Mediated Intestinal Secretion of Glibenclamide: In Vitro and In Vivo Assessments

The everted gut sac method was used to assess the role of the P-glycoprotein (P-gp) on the intestinal secretion of glibenclamide, a prototype of drug used to treat diabetic mellitus. The study included the evaluation of a P-gp modulator carbamazepine used at equimolar doses in the rat. Furthermore,...

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Detalles Bibliográficos
Autores principales:	Srirangam, P, Vidya, Sagar J
Formato:	Texto
Lenguaje:	English
Publicado:	Medknow Publications 2010
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019377/ https://www.ncbi.nlm.nih.gov/pubmed/21264098 http://dx.doi.org/10.4103/0975-1483.71632

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