Zero Order Spectrophotometric Method for Estimation of Escitalopram Oxalate in Tablet Formulations

A new, simple, fast and reliable zero order spectrophotometric method has been developed for determination of Escitalopram Oxalate in bulk and tablet dosage forms. The quantitative determination of drug was carried out using the zero order values (absorbance) measured at 238 nm. Calibration graph co...

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Detalles Bibliográficos
Autores principales: Sharma, S, Rajpurohit, H, Sonwal, C, Bhandari, A, Choudhary, VR, Jain, T
Formato: Texto
Lenguaje:English
Publicado: Medknow Publications 2010
Materias:
Pharm Analysis
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019386/
https://www.ncbi.nlm.nih.gov/pubmed/21264107
http://dx.doi.org/10.4103/0975-1483.71626
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author Sharma, S
Rajpurohit, H
Sonwal, C
Bhandari, A
Choudhary, VR
Jain, T
author_facet Sharma, S
Rajpurohit, H
Sonwal, C
Bhandari, A
Choudhary, VR
Jain, T
author_sort Sharma, S
collection PubMed
description A new, simple, fast and reliable zero order spectrophotometric method has been developed for determination of Escitalopram Oxalate in bulk and tablet dosage forms. The quantitative determination of drug was carried out using the zero order values (absorbance) measured at 238 nm. Calibration graph constructed at 238 nm was linear in concentration range of 2-20 µg/ml with correlation coefficient 0.9999. The method was found to be precise, accurate, specific, and validated as per ICH guidelines and can be used for determination of Escitalopram Oxalate in tablet formulations.
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spelling pubmed-30193862011-01-24 Zero Order Spectrophotometric Method for Estimation of Escitalopram Oxalate in Tablet Formulations Sharma, S Rajpurohit, H Sonwal, C Bhandari, A Choudhary, VR Jain, T J Young Pharm Pharm Analysis A new, simple, fast and reliable zero order spectrophotometric method has been developed for determination of Escitalopram Oxalate in bulk and tablet dosage forms. The quantitative determination of drug was carried out using the zero order values (absorbance) measured at 238 nm. Calibration graph constructed at 238 nm was linear in concentration range of 2-20 µg/ml with correlation coefficient 0.9999. The method was found to be precise, accurate, specific, and validated as per ICH guidelines and can be used for determination of Escitalopram Oxalate in tablet formulations. Medknow Publications 2010 /pmc/articles/PMC3019386/ /pubmed/21264107 http://dx.doi.org/10.4103/0975-1483.71626 Text en © Journal of Young Pharmacists http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Pharm Analysis
Sharma, S
Rajpurohit, H
Sonwal, C
Bhandari, A
Choudhary, VR
Jain, T
Zero Order Spectrophotometric Method for Estimation of Escitalopram Oxalate in Tablet Formulations
title Zero Order Spectrophotometric Method for Estimation of Escitalopram Oxalate in Tablet Formulations
title_full Zero Order Spectrophotometric Method for Estimation of Escitalopram Oxalate in Tablet Formulations
title_fullStr Zero Order Spectrophotometric Method for Estimation of Escitalopram Oxalate in Tablet Formulations
title_full_unstemmed Zero Order Spectrophotometric Method for Estimation of Escitalopram Oxalate in Tablet Formulations
title_short Zero Order Spectrophotometric Method for Estimation of Escitalopram Oxalate in Tablet Formulations
title_sort zero order spectrophotometric method for estimation of escitalopram oxalate in tablet formulations
topic Pharm Analysis
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019386/
https://www.ncbi.nlm.nih.gov/pubmed/21264107
http://dx.doi.org/10.4103/0975-1483.71626
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AT sonwalc zeroorderspectrophotometricmethodforestimationofescitalopramoxalateintabletformulations
AT bhandaria zeroorderspectrophotometricmethodforestimationofescitalopramoxalateintabletformulations
AT choudharyvr zeroorderspectrophotometricmethodforestimationofescitalopramoxalateintabletformulations
AT jaint zeroorderspectrophotometricmethodforestimationofescitalopramoxalateintabletformulations

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