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BMP promotes motility and represses growth of smooth muscle cells by activation of tandem Wnt pathways
We present a novel cell-signaling paradigm in which bone morphogenetic protein 2 (BMP-2) consecutively and interdependently activates the wingless (Wnt)–β-catenin (βC) and Wnt–planar cell polarity (PCP) signaling pathways to facilitate vascular smooth muscle motility while simultaneously suppressing...
Autores principales: | de Jesus Perez, Vinicio A., Ali, Ziad, Alastalo, Tero-Pekka, Ikeno, Fumiaki, Sawada, Hirofumi, Lai, Ying-Ju, Kleisli, Thomas, Spiekerkoetter, Edda, Qu, Xiumei, Rubinos, Laura H., Ashley, Euan, Amieva, Manuel, Dedhar, Shoukat, Rabinovitch, Marlene |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019546/ https://www.ncbi.nlm.nih.gov/pubmed/21220513 http://dx.doi.org/10.1083/jcb.201008060 |
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