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p62 targeting to the autophagosome formation site requires self-oligomerization but not LC3 binding
Autophagy is an intracellular degradation process by which cytoplasmic contents are degraded in the lysosome. In addition to nonselective engulfment of cytoplasmic materials, the autophagosomal membrane can selectively recognize specific proteins and organelles. It is generally believed that the maj...
Autores principales: | Itakura, Eisuke, Mizushima, Noboru |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
The Rockefeller University Press
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3019556/ https://www.ncbi.nlm.nih.gov/pubmed/21220506 http://dx.doi.org/10.1083/jcb.201009067 |
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