Conditional meta-analysis stratifying on detailed HLA genotypes identifies a novel type 1 diabetes locus around TCF19 in the MHC

The human leukocyte antigen (HLA) class II genes HLA-DRB1, -DQA1 and -DQB1 are the strongest genetic factors for type 1 diabetes (T1D). Additional loci in the major histocompatibility complex (MHC) are difficult to identify due to the region’s high gene density and complex linkage disequilibrium (LD...

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Detalles Bibliográficos
Autores principales: Cheung, Yee Him, Watkinson, John, Anastassiou, Dimitris
Formato: Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020293/
https://www.ncbi.nlm.nih.gov/pubmed/21076979
http://dx.doi.org/10.1007/s00439-010-0908-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020293/
https://www.ncbi.nlm.nih.gov/pubmed/21076979
http://dx.doi.org/10.1007/s00439-010-0908-2

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