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Focused ultrasound-mediated bbb disruption is associated with an increase in activation of AKT: experimental study in rats
BACKGROUND: The Blood Brain Barrier (BBB) maintains the homeostasis of central nervous system by preventing the free passage of macromolecules from the systemic circulation into the brain. This normal physiological function of the BBB presents a challenge for delivery of therapeutic compounds into t...
Autores principales: | , , , |
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Formato: | Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020671/ https://www.ncbi.nlm.nih.gov/pubmed/21078165 http://dx.doi.org/10.1186/1471-2377-10-114 |