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Focused ultrasound-mediated bbb disruption is associated with an increase in activation of AKT: experimental study in rats

BACKGROUND: The Blood Brain Barrier (BBB) maintains the homeostasis of central nervous system by preventing the free passage of macromolecules from the systemic circulation into the brain. This normal physiological function of the BBB presents a challenge for delivery of therapeutic compounds into t...

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Detalles Bibliográficos
Autores principales:	Jalali, Shahrzad, Huang, Yuexi, Dumont, Daniel J, Hynynen, Kullervo
Formato:	Texto
Lenguaje:	English
Publicado:	BioMed Central 2010
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020671/ https://www.ncbi.nlm.nih.gov/pubmed/21078165 http://dx.doi.org/10.1186/1471-2377-10-114

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