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Translation reinitiation and development are compromised in similar ways by mutations in translation initiation factor eIF3h and the ribosomal protein RPL24

BACKGROUND: Within the scanning model of translation initiation, reinitiation is a non-canonical mechanism that operates on mRNAs harboring upstream open reading frames. The h subunit of eukaryotic initiation factor 3 (eIF3) boosts translation reinitiation on the uORF-containing mRNA coding for the...

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Detalles Bibliográficos
Autores principales: Zhou, Fujun, Roy, Bijoyita, von Arnim, Albrecht G
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020687/
https://www.ncbi.nlm.nih.gov/pubmed/20799971
http://dx.doi.org/10.1186/1471-2229-10-193