Identification of Neuronal RNA Targets of TDP-43-containing Ribonucleoprotein Complexes

TAR DNA-binding protein 43 (TDP-43) is associated with a spectrum of neurodegenerative diseases. Although TDP-43 resembles heterogeneous nuclear ribonucleoproteins, its RNA targets and physiological protein partners remain unknown. Here we identify RNA targets of TDP-43 from cortical neurons by RNA...

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Detalles Bibliográficos
Autores principales: Sephton, Chantelle F., Cenik, Can, Kucukural, Alper, Dammer, Eric B., Cenik, Basar, Han, YuHong, Dewey, Colleen M., Roth, Frederick P., Herz, Joachim, Peng, Junmin, Moore, Melissa J., Yu, Gang
Formato: Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2011
Materias:
Neurobiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020728/
https://www.ncbi.nlm.nih.gov/pubmed/21051541
http://dx.doi.org/10.1074/jbc.M110.190884

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