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Bone cancer induces a unique central sensitization through synaptic changes in a wide area of the spinal cord

BACKGROUND: Chronic bone cancer pain is thought to be partly due to central sensitization. Although murine models of bone cancer pain revealed significant neurochemical changes in the spinal cord, it is not known whether this produces functional alterations in spinal sensory synaptic transmission. I...

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Detalles Bibliográficos
Autores principales: Yanagisawa, Yoshikazu, Furue, Hidemasa, Kawamata, Tomoyuki, Uta, Daisuke, Yamamoto, Jun, Furuse, Shingo, Katafuchi, Toshihiko, Imoto, Keiji, Iwamoto, Yukihide, Yoshimura, Megumu
Formato: Texto
Lenguaje:English
Publicado: BioMed Central 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020802/
https://www.ncbi.nlm.nih.gov/pubmed/20602757
http://dx.doi.org/10.1186/1744-8069-6-38