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Autophagy facilitates glycolysis during Ras-mediated oncogenic transformation

The protumorigenic functions for autophagy are largely attributed to its ability to promote cancer cell survival in response to diverse stresses. Here we demonstrate an unexpected connection between autophagy and glucose metabolism that facilitates adhesion-independent transformation driven by a str...

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Detalles Bibliográficos
Autores principales: Lock, Rebecca, Roy, Srirupa, Kenific, Candia M., Su, Judy S., Salas, Eduardo, Ronen, Sabrina M., Debnath, Jayanta
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020913/
https://www.ncbi.nlm.nih.gov/pubmed/21119005
http://dx.doi.org/10.1091/mbc.E10-06-0500