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Ubiquitin-dependent degradation of HDAC4, a new regulator of random cell motility

HDAC4 (histone deacetylase 4) belongs to class IIa of histone deacetylases, which groups important regulators of gene expression, controlling pleiotropic cellular functions. Here we show that, in addition to the well-defined nuclear/cytoplasmic shuttling, HDAC4 activity is modulated by the ubiquitin...

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Detalles Bibliográficos
Autores principales: Cernotta, Nadia, Clocchiatti, Andrea, Florean, Cristina, Brancolini, Claudio
Formato: Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020922/
https://www.ncbi.nlm.nih.gov/pubmed/21118993
http://dx.doi.org/10.1091/mbc.E10-07-0616

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