Cargando…
Proteins Encoded in Genomic Regions Associated with Immune-Mediated Disease Physically Interact and Suggest Underlying Biology
Genome-wide association studies (GWAS) have defined over 150 genomic regions unequivocally containing variation predisposing to immune-mediated disease. Inferring disease biology from these observations, however, hinges on our ability to discover the molecular processes being perturbed by these risk...
Autores principales: | Rossin, Elizabeth J., Lage, Kasper, Raychaudhuri, Soumya, Xavier, Ramnik J., Tatar, Diana, Benita, Yair, Cotsapas, Chris, Daly, Mark J. |
---|---|
Formato: | Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2011
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020935/ https://www.ncbi.nlm.nih.gov/pubmed/21249183 http://dx.doi.org/10.1371/journal.pgen.1001273 |
Ejemplares similares
-
Identifying Relationships among Genomic Disease Regions: Predicting Genes at Pathogenic SNP Associations and Rare Deletions
por: Raychaudhuri, Soumya, et al.
Publicado: (2009) -
An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia
por: Benita, Yair, et al.
Publicado: (2009) -
Network Analysis of Genome-Wide Selective Constraint Reveals a Gene Network Active in Early Fetal Brain Intolerant of Mutation
por: Choi, Jinmyung, et al.
Publicado: (2016) -
Disproportionate Contributions of Select Genomic Compartments and Cell Types to Genetic Risk for Coronary Artery Disease
por: Won, Hong-Hee, et al.
Publicado: (2015) -
Genome‐wide association studies of multiple sclerosis
por: Cotsapas, Chris, et al.
Publicado: (2018)