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Identification of Genes that Elicit Disuse Muscle Atrophy via the Transcription Factors p50 and Bcl-3

Skeletal muscle atrophy is a debilitating condition associated with weakness, fatigue, and reduced functional capacity. Nuclear factor-kappaB (NF-κB) transcription factors play a critical role in atrophy. Knockout of genes encoding p50 or the NF-κB co-transactivator, Bcl-3, abolish disuse atrophy an...

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Detalles Bibliográficos
Autores principales: Wu, Chia-Ling, Kandarian, Susan C., Jackman, Robert W.
Formato: Texto
Lenguaje:English
Publicado: Public Library of Science 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3020958/
https://www.ncbi.nlm.nih.gov/pubmed/21249144
http://dx.doi.org/10.1371/journal.pone.0016171